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ASTROPHYSICS

  

ASTROPHYSICS: Guiding the Gravity Wave Search

David Voss

General relativity predicts that when massive objects crash into each other, they should emit ripples in the spacetime fabric called gravitational waves. Detection of these waves is an eagerly pursued but as yet elusive goal. The merger of binary black holes is one example of a powerful event that has been well studied theoretically in the hopes of identifying a clear gravitational wave signature. Supernovae and collapsing stars may also provide strong gravitational wave signals and thus an enlarged set of targets for detection. Dimmelmeier et al. performed computer simulations of fusion-burning stars progressing toward their golden years as nonburning neutron stars. The authors paid special attention to the particularly strong gravitational wave burst expected just after collapse, as the in-falling material slams against the hard iron core of the dying star. Exploring a wide range of parameters, they found a clear set of waveform templates that should expedite the search for gravitational waves. -- DV

Phys. Rev. Lett. 98, 251101 (2007).

 
 
 

When Galaxies Collide

Figure 1 Large galaxies grow through collisions of many smaller ones (see the Perspective by Coppi). When two galaxies collide, the giant supermassive black holes that sit in their centers eventually meet and spin around one another as a binary system. In the absence of any braking forces, the black holes would continue to orbit one another for at least billions of years. However, large galaxy cores host single black holes, so other astrophysical processes must help the black hole pairs coalesce more rapidly. Mayer et al. (p. 1874, published online 7 June) performed hydrodynamical simulations which show that gas within merging galaxies slows their black holes enough so that they can bind together within just 1 million years. In simulating the decay of a binary black hole system within a gas-rich galaxy that has recently formed from the merger of two smaller spirals, the authors tracked the black holes before their coalescence to within a few light years from each other. Max et al. (p. 1877, published online 17 May) have obtained very-high-resolution infrared images of a nearby pair of spiral galaxies called NGC 6240 that have already collided--their stars and gas wrapping are around one another. Using adaptive optics techniques on the Keck telescope in Hawaii, they pinpoint the positions of two black holes that once dotted the centers of the original galaxies. Around the black holes, cones of gas and new stars are seen that may have formed in the wake of the black holes as they spiraled in toward one another. This separation indicates the effects of dynamical friction stirring the gas as it mixes together.

CREDIT: MAYER ET AL.

BOY SCOUT SLOGAN: "BE PREPAIRED"

 
"The world is a dangerous place to live, not because of the people who are evil, but because of the people who don't do anything about it." - Albert Einstein
 
 
 Threat to world peace: The possibility of a US attack on Iran
 
Excerpts of presentation, Vancouver 9/11 Truth Conference
 
By Prof. Peter Dale Scott
 
"I have been speaking in public for 60 years, but this is perhaps the most important topic I have ever spoken about." "I want to talk about the threat to world peace, and the possibility of a US attack, possibly a nuclear attack, on Iran."
http://www.informationclearinghouse.info/article17926.htm

BIOCHEMISTRY

 

BIOCHEMISTRY: Bacterial Drug Design

Gilbert Chin

The most effective weapons for fighting bacterial infections are those that bacteria use against each other. One tactic for combating the spread of drug-resistant strains is to use multiple drugs, such as the combination of dalfopristin (a type A streptogramin) and quinupristin (a type B streptogramin). The former blocks an early step in ribosomal protein synthesis, whereas the latter blocks a late step.

Korczynska et al. describe the crystal structure of virginiamycin B lyase (Vgb) in complex with quinupristin (fortuitously, a chock of dalfopristin immobilizes two Vgb molecules in the crystal, but this interaction is without an in vivo correlate). Vgb inactivates the cyclic peptide antibiotic by catalyzing a linearization, and structure-based mutagenesis supports the mechanistic proposal that ring opening occurs not via hydrolysis of an ester but by means of a C-O lyase reaction. The detailed view of quinupristin binding to Vgb is consistent with its versatility in detoxifying natural and semisynthetic type B streptogramins--the known modifications all point into the solvent and away from the active site. A comparison of this complex with that of quinupristin bound to the 50S ribosomal subunit may guide design efforts aimed at reducing its affinity for Vgb without lessening its ardor for the ribosome. -- GJC

Proc. Natl. Acad. Sci. U.S.A. 104, 10388 (2007).